<b>General measures</b><br>ffIV fluids ffControl of temperature ffNutrition support (NGT if necessary) ffMonitoring of vitals and urinary output}<b>If known focus of infection, treat immediately with IV antibiotics as per guidelines. If unknown focus, give:</b><br><b>Adult</b>ffGentamicin 7 mg/kg IV every 24 hours or 1.5-2 mg/kg IV or IM every 8 hours ffPlus either cloxacillin 2 g IV every 4-6 hours ffOr chloramphenicol 750 mg IV every 6 hours<br><b>Child</b><br>ffGentamicin 3.5-4 mg/kg IV every 8 hours (neonate: every 8-12 hours) ffPlus either: Ceftriaxone 50 mg/kg every 8 hours (< 7 days old: every 12 hours) ffOr cloxacillin 50 mg/kg IV every 4-6 hours ffOr benzylpenicillin 50,000 IU/kg IV every 4-6 hours